The A14 westbound was closed near Bury St Edmunds on Tuesday evening after a car ended up on its roof.
The incident took place at junction 41 for Risby West.
One person was taken to hospital with injuries that were not thought to be life -threatening or life-changing.
Highways England warned of long delays of up to 30 mins on the road while the incident was dealt with.
Diversions were put in place to help traffic move around the area with drivers being directed off the carriageway at junction 42.
A volunteer doctor from the Suffolk Accident Rescue Service (SARS) charity attended the crash, which happened at about 9.30pm.
The SARS doctor assessed a male patient, who had sustained a leg injury, before he was taken to hospital by land ambulance.
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